Боли в области позвоночника как одно из наиболее распространенных клинических нарушений. Причины развития болевого синдрома в нижней части спины; изменения в мезпозвоночных дисках. Медикаментозная терапия и другие способы подавления болевого синдрома.
Аннотация к работе
Боли в области позвоночника относятся к числу наиболее распространенных клинических нарушений. Боли в позвоночнике принято подразделять на острые и хронические. Повторные эпизоды в течение ближайшего года возникают у 20-44% больных, а в общей сложности рецидивы наблюдаются в 85% случаев. Зачастую болевой синдром не прекращается полностью, и у больных периодически возникают обострения хронических БНЧС. В целом примерно 80% населения развитых стран на протяжении жизни отмечает эпизоды таких болей [21].
Список литературы
1. Болезни нервной системы. Том 1. Под ред. Н.Н.Яхно, Д.Р. Штульмана. Москва, Медицина 2001, 477 стр.
2. Anderson JA. Epidemiological aspects of back pain. Journal of the Society of Occupational Medicine 1986;36:90-4.
3. Bogduk N. Management of chronic low back pain. Med J Aust. 2004 Jan 19;180(2):79-83.
4. Cannon DT, Aprill CN. Lumbosacral epidural steroid injections. Arch Phys Med Rehabil Sl(suppl): S87-S98, 2000.
5. Carroll LJ, Cassidy JD, Cote P. Depression as a risk factor for onset of an episode of troublesome neck and low back pain. Pain. 2004 Jan;107(1-2):134-9.
6. Dreyer SJ, Dreyfuss P, Cole AJ. Zygapophyseal (facet) joint injections. Phys Med Rehabil Clin North Am 6:715-741, 1995.
7. Dunlop RB, Adams MA, Hutton WC. Disc space narrowing and the lumbar facet joints. J Bone Joint Surg Br 66:706-710, 1984.
8. Ehrlich GE. Low back pain. Bull World Health Organ. 2003;81(9):671-6. Epub 2003 Nov 14.
9. Elders LA, Burdorf A. Prevalence, incidence, and recurrence of low back pain in scaffolders during a 3-year followup study. Spine. 2004 Mar 11;29(6):E101-6.
10. Fernandes JC, Martel-Pelletier J, Pelletier JP. The role of cytokines in osteoarthritis pathophysiology. Biorheology 2002;39(1-2):237-46
11. Freemont AJ, Peacock ТЕ, Goupille P, et al. Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet 350:178-181, 1997.
12. Geisser ME, Haig AJ, Wallbom AS, Wiggert EA. Pain-related fear, lumbar flexion, and dynamic EMG among persons with chronic musculoskeletal low back pain. Clin J Pain. 2004 Mar-Apr;20(2):61-9.
13. Giesecke T, Gracely RH, Grant MA, Nachemson A, Petzke F, Williams DA, Clauw DJ. Evidence of augmented central pain processing in idiopathic chronic low back pain. Arthritis Rheum. 2004 Feb;50(2):613-23.
14. Ianuzzi A, Little JS, Chiu JB, Baitner A, Kawchuk G, Khalsa PS. Human lumbar facet joint capsule strains: I. During physiological motions. Spine J. 2004 Mar-Apr;4(2):141-52.
15. Inufusa A, An HS, Lim TH, et al. Anatomic changes of the spinal canal and intervertebral foramen associated with flexion-extension movement. Spine 21:2412-2420, 1996.
16. Jin K, Sorock GS, Courtney TK. Prevalence of low back pain in three occupational groups in Shanghai, People’s Republic of China. J Safety Res. 2004;35(1):23-8.
17. Johnson WE, Roberts S. Human intervertebral disc cell morphology and cytoskeletal composition: a preliminary study of regional variations in health and disease. J Anat. 2003 Dec;203(6):605-12.
18. Jurna I. Analgesic and analgesia-potentiating action of B vitamins. Schmerz. 1998 Apr 20;12(2):136-41.
19. Katz N, Ju WD, Krupa DA, Sperling RS, Bozalis Rodgers D, Gertz BJ, Gimbel J, Coleman S, Fisher C, Nabizadeh S, Borenstein D; Vioxx Chronic Low Back Pain Study Group. Efficacy and safety of rofecoxib in patients with chronic low back pain: results from two 4-week, randomized, placebo-controlled, parallel-group, double-blind trials. Spine. 2003 May 1;28(9):851-8
20. Leboeuf-Yde C. Back pain-individual and genetic factors. J Electromyogr Kinesiol. 2004 Feb;14(1):129-33.
21. Lee D. Low back pain intervention: conservative or surgical? J Surg Orthop Adv. 2003 Winter;12(4):200-2.
22. Limon S, Valinsky LJ, Ben-Shalom Y. Children at risk: risk factors for low back pain in the elementary school environment. Spine. 2004 Mar 11;29(6):697-702.
23. Lindblad S., Hedfors E. Arthroscopic and immunohistologic characterization of knee joint synovitis in osteoarthritis. Arthritis rheum. 1987, 30, 1081-1088
24. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000 May-Jun;4(3):53-8.
25. Medina Santillan R, Reyes Garcia G, Sanchez Mejia JL, Mateos Garcia E. Dexamethasone alone versus dexamethasone plus complex B vitamins in the therapy of low back pain. Proc West Pharmacol Soc. 2000;43:69-70.
26. Nygaard OP, Mellgren SI, Osterud B. The inflammatory properties of contained and noncontained lumbar disc herniation. Spine 22:2484-2488, 1997.
27. Omokhodion FO. Low back pain in an urban population in Southwest Nigeria. Trop Doct. 2004 Jan;34(1):17-20.
28. Osti OL, Vernon-Roberts B, Moore R, Eraser RD. Annular tears and disc degeneration in the lumbar spine. A postmortem study of 135 discs. J Bone Joint Surg Br 74:678-682, 1992.
29. Palangio M, Morris E, Doyle RT Jr, Dornseif BE, Valente TJ. Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of moderate or severe acute low back pain. Clin Ther. 2002 Jan;24(1):87-99.
30. Piperno M, Hellio le Graverand MP, et al. Phospholipase A2 activity in herniated lumbar discs. Clinical correlations and inhibition by piroxicam. Spine 22:2061-2065, 1997.
31. Rainville J, Hartigan C, Martinez E, Limke J, Jouve C, Finno M. Exercise as a treatment for chronic low back pain. Spine J. 2004 Jan-Feb;4(1):106-15.
32. Rang JD, Stefanovic-Racic M, Mclntyre LA, et al. Toward a biochemical understanding of human in tervertebral disc degeneration and herniation. Contributions of nitric oxide, interleukins, prostaglandin E2, and matrix metalloproteinases. Spine 22:1065-1073, 1997.
33. Schattenkirchner M, Milachowski KA. A double-blind, multicentre, randomised clinical trial comparing the efficacy and tolerability of aceclofenac with diclofenac resinate in patients with acute low back pain. Clin Rheumatol. 2003 May;22(2):127-35.
34. Schonstrom N, Bolender NF, Spengler DM. The pathomorphology of spinal stenosis as seen on CT scans of the lumbar spine. Spine 10:806-811, 1985.
35. Steinberg EL, Luger E, Arbel R, Menachem A, Dekel S. A comparative roentgenographic analysis of the lumbar spine in male army recruits with and without lower back pain. Clin Radiol. 2003 Dec;58(12):985-9.
36. Strumpf M, Linstedt U, Wiebalck A, Zenz M. Treatment of low back pain-significance, principles and danger. Schmerz. 2001 Dec;15(6):453-60.
37. Takahashi H, Suguro T, Okazima Y, et al. Inflammatory cytokines in the herniated disc of the lumbar spine. Spine 21:218-224, 1996.
38. Takahashi K, Kagechika K, Takino T, et al. Changes in epidural pressure during walking in patients with lumbar spinal stenosis. Spine 20:2746-2749, 1995.
39. Takahashi K, Shima I, Porter RW. Nerve root pressure in lumbar disc herniation. Spine 24:2003-2006, 1999.
40. Takata K, Inoue S, Takahashi K, Ohtsuka Y. Swelling of the cauda equina in patients who have herniation of a lumbar disc. A possible pathogenesis of sciatica. J Bone Joint Surg Am 70:361-368, 1988.
41. Toussirot E, Wendling D. Current guidelines for the drug treatment of ankylosing spondylitis. Drugs. 1998 Aug;56(2):225-40.
42. Tveito TH, Hysing M, Eriksen HR. Low back pain interventions at the workplace: a systematic literature review. Occup Med (Lond). 2004 Jan;54(1):3-13.
43. van den Bosch MA, Hollingworth W, Kinmonth AL, Dixon AK. Evidence against the use of lumbar spine radiography for low back pain. Clin Radiol. 2004 Jan;59(1):69-76.
44. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ. 2003;81(9):646-56. Epub 2003 Nov 14.