Изучение результатов комбинированной терапии с использованием соматотропных и психотропных лечебных средств: циталопрама (ингибитора серотонина) и бензодиазепина, для лечения больных артериальной гипертонией с метаболическими нарушениями и депрессией.
Аннотация к работе
Psychopharmacotherapy of patients with arterial hypertension complicated with metabolic disturbances and depressionThirty-six patients with arterial hypertension complicated with disturbances of carbohydrate metabolism (from changes of tolerance to glucose to diabetes mellitus type II), lipid metabolism (obesity of different degree) and depression have been studied. In 23 cases (main group), a combined therapy with somatotropic and psychotropic drugs was used while 13 patients were (control group) treated only with somatotropic medications. Citalopram, a selective inhibitor of serotonin reuptake, was the main psychopharmacological drug used in the treatment of the main group. Patient’s state was assessed by the results of the somatic and psychopathological examination using psychometric scales and by a number of indices obtained in the instrumental and laboratory (biochemical etc) study. The results suggest the higher efficacy of the combined therapy by all parameters - arterial pressure, indices of carbohydrate and lipid metabolism, severity of affective disorders.