A feature of the use of non-steroidal anti-inflammatory drugs for osteochondrosis of the spine. The advisability of using a combination of omeprazole and mexicor to correct the negative effects of drugs that occur during long-term treatment of patients.
Аннотация к работе
Национальный Исследовательский Мордовский Государственный Университет им. Н.П. Огарева ОПЫТ ПРИМЕНЕНИЯ МЕКСИКОРА В СХЕМЕ ТЕРАПИИ БОЛЬНЫХ ОСТЕОХОНДРОЗОМ Семелева Е.В. г. Саранск NSAIDs have become an integral part of modern person’s life and a factor of the environment surrounding him [4, P. 3452]. This trend has become particularly noticeable in the last decade due to general “aging” of the human population and, as a consequence, an increase in the number of elderly people suffering from chronic pain syndrome. The pathology of the gastrointestinal tract that occurs after ingestion of NSAIDs, in fact, has gone beyond the complications of a particular type of drug therapy [3, P. 2227]. Nearly all NSAIDs (with different frequencies), regardless of their chemical structure, a dosage form and a method of administering the medication, cause gastro toxic effects. Duration of a course treatment was 14 days. The disease duration of the patients in the first group was 10,3 ± 1 years, the average age was 55 ± 0,8 years old; the second group - 9.7 ± 1 years, the average age - 57 ± 1 years old; the third group - 10.8 ± 1 years, the average age - 58 ± 1 years old. We took into account the complaints related to the underlying disease: pain, pelvic disorders, numbness, motion limitations, extremities weakness, dyspeptic symptoms (heartburn, acid regurgitation, nausea, chest pain associated with food intake, a salty sour taste in the mouth; stool disorders (constipation / diarrhea); unpleasant / painful sensations in the stomach after eating, (tympanitic resonance/ abdominal distention), disorders of the cardiovascular system (CVS) (high blood pressure, edema, chest pain caused by exercise). The dynamics of systolic and diastolic blood pressure (SBP and DBP), heart rate (HR) were also taken into account. Each of the complaints, depending on its intensity, was evaluated from 0 to 4 points by the patients. steroidal osteochondrosis spine drug The patients in the examined groups definitely did not differ on the initial analyzed parameters. The disease duration of the patients from the first group was 10,3 ± 1 years old, body mass index (BMI) was on average 29 ± 0,4 kg / m2. A course treatment for this group of the patients (the average age was 55 ± 0,8 years old) was accompanied by a significant decrease in the number of points connected with complaints related to the underlying disease (from 7,4 ± 0,3 to 4 ± 0,1).